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menH [2017-06-16 20:27:46]
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menH [2017-06-16 20:27:46]

menaquinone biosynthesis methyltransferase
Locus
BSU22750
Isoelectric point
8.17
Molecular weight
26.43 kDa
Protein length
233 aa Sequence Blast
Gene length
699 bp Sequence Blast
Function
biosynthesis of menaquinone
Product
menaquinone biosynthesis methyltransferase
Essential
no
E.C.
2.1.1.163
Synonyms
gerCB,menG
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis of menaquinone
  • Lifestyles → Exponential and early post-exponential lifestyles → Biofilm formation → Other proteins required for biofilm formation

    • Gene

    Coordinates
    2,382,907 → 2,383,608

    Phenotypes of a mutant

  • essential according to Kobayashi et al. ; however, inactivation reported by Meeske et al. and Block et al.
  • inactivation of menH reduces sporulation efficiency to 12.7% that of wild type cells PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • S-adenosyl-L-methionine + demethylmenaquinol = s-adenosyl-L-homocysteine + menaquinol (according to Swiss-Prot)

    • Structure

  • 1OBW (from Saccharomyces cerevisiae, 31% identity) PubMed

    • Expression and Regulation

    Operons

    Genes
    hepS-menH-hepT-ndk
    Description
    PubMed
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    Biological materials

    Mutant

  • BKE22750 (*menH::erm trpC2*) available at the Bacillus Genetic Stock Center
  • BKK22750 (*menH::kan trpC2*) available at the Bacillus Genetic Stock Center

    • References

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